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          Chromatography packing for Huperzine extraction, separation and purification SKP-10-4100 SKR-10-4100

          Classification:
          Separation and purification process development
          Author:
          Source:
          Release time:
          2019/09/24 17:27
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          [Abstract]:
          Huperzine A is a potent and reversible cholinesterase inhibitor, which is good for treating myasthenia gravis, improving memory decline in the elderly, and improving the memory and cognitive behavioral functions of Alzheimer's patients.

          Chromatography packing for extraction, separation and purification of Huperzine A (Huperzine) SKP-10-4100 SKR-10-4100

          Huperzine A is a potent and reversible cholinesterase inhibitor, which is good for treating myasthenia gravis, improving memory decline in the elderly, and improving the memory and cognitive behavioral functions of Alzheimer's patients. The curative effect is the second-generation acetylcholine drug recognized internationally. The content of Huperzine A in plants is extremely low, only about two ten thousandths. It is difficult to use traditional extraction, separation and purification methods to increase the purity of Huperzine A to 99% under the condition of ensuring high yield.

          Shandong Bona Biotechnology Group Co., Ltd. has developed two kinds of fillers, SKP-10-4100 and SKR-10-4100 on the basis of years of research. On the basis of ensuring high product yield, the crude huperzine A can be purified to 99% by two-step chromatography. Huperzine A is an alkaloid, and the crude product is generally extracted by acid-water leaching and enriched by cation exchange resin adsorption.

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